Subclinical ketosis risk prediction in dairy cows based on prepartum metabolic indices

ABSTRACT Ketosis can seriously impair cow performance. This study detected changes in prepartum blood metabolic parameters for predicting postpartum ketosis occurrence dairy cows. Body condition score (BCS) was assessed before and after delivery. Blood samples of 63 cows were collected from 10 days calving to measure including β-hydroxybutyric acid (BHBA), non-esterified fatty (NEFA), glucose (GLU), total bilirubin (TBIL), direct (DBIL), indirect (IBIL), protein (TP), albumin (ALB), globulin (GLO), alanine aminotransferase (ALT), aspartate (AST). There a subclinical incidence 42.25%. Compared with prepartum, plasma, levels BHBA, AST, NEFA significantly increased postpartum, AST (R=0.57) (R=0.45) showed significant positive correlation postpartum. Plasma GLU level decreased negatively correlated (R=-0.21). Receiver operating characteristic curve analysis revealed BSC < 2.88, plasma > 68.0 U/L, 3.97mmol/L, 0.27mmol/L, BHBA 0.43mmol/L, indicating high risk These be used as indicators predict the